Related Experiment Video
Updated: Jan 26, 2026
07:29
HPLC Coupled with Chemical Fingerprinting for Multi-Pattern Recognition for Identifying the Authenticity of Clematidis Armandii Caulis
Published on: November 11, 2022
2.4K
An Introduction to RA21: Taking Authentication Beyond IP Addresses.
1a Mayo Clinic Libraries, Mayo Clinic , Rochester , Minnesota , USA.
Medical Reference Services Quarterly
|April 4, 2019
Summary
Libraries are exploring Resource Access for the 21st Century (RA21) to improve electronic resource authentication. This new protocol aims to replace outdated IP address authentication methods for better user access.
Area of Science:
- Library and Information Science
- Digital Authentication Technologies
Background:
- Libraries traditionally use Internet Protocol (IP) addresses for electronic resource access control.
- IP address authentication is becoming less accurate for verifying user affiliation with institutions.
Purpose of the Study:
- To introduce Resource Access for the 21st Century (RA21) as a potential solution.
- To examine the problems RA21 aims to solve and potential new challenges it may introduce.
Main Methods:
- Exploration of the RA21 protocol.
- Analysis of current IP authentication limitations.
- Discussion of potential impacts of RA21 implementation.
Main Results:
- IP address authentication is increasingly unreliable for library resource access.
- RA21 is being developed as a successor protocol by industry and academic stakeholders.
Conclusions:
- RA21 presents a new approach to electronic resource access authentication.
- Further investigation is needed to understand the full implications and effectiveness of RA21.
Related Concept Videos
01:25Strategies for Assessing and Addressing Confounding
374
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
374
01:21EPS and iPS Cells in Disease Research
3.4K
Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
3.4K
01:22iPS Cell Differentiation
3.1K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
3.1K
01:29Somatic to iPS Cell Reprogramming
2.6K
Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
2.6K
01:32Chromatin Modification in iPS Cells
2.2K
Chromatin modification alters gene expression; therefore, scientists can add histone-modifying enzymes, histone variants, and chromatin remodeling complexes to somatic cells to aid reprogramming into pluripotent stem (iPS) cells.
Compact chromatin makes reprogramming difficult. Enzymes, such as histone demethylases and acetyltransferases, are often added during reprogramming to loosen the chromatin, making the DNA more accessible to transcription factors. Molecules that inhibit histone...
Compact chromatin makes reprogramming difficult. Enzymes, such as histone demethylases and acetyltransferases, are often added during reprogramming to loosen the chromatin, making the DNA more accessible to transcription factors. Molecules that inhibit histone...
2.2K
01:11Introduction to R
4.3K
R is a powerful software environment for statistical computing and graphics. Originating as an implementation of the S language, developed at Bell Laboratories, R has evolved into a robust, open-source statistical software favored by statisticians and data scientists worldwide. Its comprehensive suite includes data manipulation, calculation, and graphical display capabilities, making it versatile for data analysis and visualization. Its programming language is at the core of R's...
4.3K