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Updated: Jan 26, 2026

An Educational Video Demonstration of How to Prone a Critically Ill Intubated Patient
Published on: November 30, 2022
Noninvasive ventilation and renal replacement therapy in do-not-intubate order critically ill patients: A brief
Vito Catalanotti1, Lara Pisani2, Sara Betti3
1Respiratory Unit, Università Magna Graecia, Catanzaro, Italy.
Introduction:
Multiple organ failure has been considered a contraindication for noninvasive ventilation (NIV).
Materials And Methods:
We described the outcome of Do-not-Intubate (DNI) patients with acute respiratory failure, treated with NIV and, subsequently, necessitating renal replacement therapy (RRT).
Results And Discussion:
Seven patients admitted to our Respiratory Intensive Care Unit, developed Acute Kidney Injury (AKI) during NIV treatment and received RRT for 12.8 ± 8 days together with NIV. All the patients but one, discontinued renal support because they regained a satisfactory urinary output; nevertheless mortality rate was high (71%).
Conclusion:
Our data suggest that RRT could be feasible together with NIV. RRT was associated with an acute improvement in renal function but did not modify the mortality rate.
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