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Published on: August 19, 2020
Complications During Continuous Renal Replacement Therapy in Critically Ill Neonates.
Saeko Nishimi1, Hiroshi Sugawara1, Chinatsu Onodera1
1Department of Pediatrics, School of Medicine, Iwate Medical University, Morioka, Japan.
Continuous renal replacement therapy (CRRT) in critically ill neonates can cause complications like hypotension and hypothermia. Analyzing these issues is key to ensuring safe CRRT for newborns.
Area of Science:
- Neonatal Intensive Care
- Pediatric Nephrology
- Critical Care Medicine
Background:
- Continuous renal replacement therapy (CRRT) is increasingly used in critically ill neonates due to advancements.
- Understanding CRRT-related complications in this vulnerable population is crucial for patient safety.
Purpose of the Study:
- To examine the complications associated with CRRT in neonates.
- To identify factors contributing to a safer CRRT protocol for newborns.
Main Methods:
- Retrospective study design.
- Review of clinical records from 2009-2017.
- Analysis of 70 CRRT sessions in eight neonates.
Main Results:
- High incidence of intradialytic hypotension (IDH) (55.7%), often occurring early in treatment.
- Frequent body temperature decline (70.5%) during CRRT sessions.
- Significant thrombocytopenia observed in 42.9% of sessions.
Conclusions:
- Key complications of neonatal CRRT include early IDH, hypothermia, and thrombocytopenia.
- Further analysis of these complications is necessary to develop safer CRRT practices for neonates.
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