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Sensory Perception: Organization of the Somatosensory System01:11

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The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
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The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
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Cardiac output (CO) is an integral aspect of human physiology, reflecting the heart's efficiency and responsiveness to the body's needs. It represents the volume of blood that the left or right ventricle ejects into the aorta or pulmonary trunk each minute. The CO is calculated by multiplying the heart rate (HR)—the number of heartbeats per minute—by the stroke volume (SV)—the amount of blood pumped out with each heartbeat.
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Embolic Middle Cerebral Artery Occlusion MCAO for Ischemic Stroke with Homologous Blood Clots in Rats
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Somatosensory Deficits After Ischemic Stroke.

Simon S Kessner1, Eckhard Schlemm1, Bastian Cheng1

  • 1From the Department of Neurology (S.S.K., E.S., B.C., C.G., G.T.), University Medical Center Hamburg-Eppendorf, Germany.

Stroke
|April 5, 2019
PubMed
Summary

Somatosensory deficits are common after ischemic stroke but mostly recover within 12 months. While associated with long-term outcomes, motor deficits are the primary driver of disability.

Keywords:
lesion symptom mappingmagnetic resonance imagingsomatosensationstroke

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Area of Science:

  • Neuroscience
  • Neurology
  • Rehabilitation Medicine

Background:

  • Somatosensory deficits are prevalent in 50-80% of stroke survivors.
  • Deficit location correlates with infarct site, but long-term lesion effects are understudied.

Purpose of the Study:

  • To investigate the long-term impact of ischemic stroke lesions on somatosensory performance.
  • To determine the association between acute somatosensory deficits and 12-month functional outcomes.

Main Methods:

  • Prospective observational study of 101 ischemic stroke patients.
  • Voxel-based lesion-symptom mapping using MRI infarct lesions.
  • Bilateral somatosensory testing at acute stage, 3, and 12 months post-stroke.

Main Results:

  • 59.4% of patients had somatosensory impairment; light touch was most affected.
  • Significant recovery observed by 3 months, with minor gains by 12 months.
  • Lesions in somatosensory cortex and insula correlated with deficits; motor deficits predicted long-term function.

Conclusions:

  • Somatosensory deficits are frequent post-ischemic stroke but show substantial recovery.
  • Lesion location in somatosensory cortex and insula is linked to deficits.
  • Motor deficits, not somatosensory deficits, independently predict long-term functional outcomes.