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Left ventricular apical hypertrophy in a transplanted heart: a case report
Uzochukwu Ibe1, Kathir Balakumaran2, Sabeena Arora3
1Department of Internal Medicine, St. Mary's hospital, 56 Franklin street, Waterbury, CT, 06716, USA. ibeben31@gmail.com.
BMC Cardiovascular Disorders
|April 5, 2019
Summary
This case report details apical hypertrophic cardiomyopathy (ApHCM) in a heart transplant recipient 17 years post-transplant. It highlights a rare occurrence of ApHCM in immunosuppressed patients, prompting further research into associated risks and prognosis.
Area of Science:
- Cardiology
- Transplant Medicine
- Cardiovascular Imaging
Background:
- Left ventricular apical hypertrophic cardiomyopathy (ApHCM) is a rare form of hypertrophic cardiomyopathy characterized by apical thickening.
- ApHCM was first described in Japan in 1976, with characteristic ECG and imaging findings.
Observation:
- A 54-year-old male, 17 years post-orthotropic heart transplant, presented with palpitations and lightheadedness.
- Investigations revealed elevated cardiac biomarkers, EKG changes, and echocardiogram findings of apical hypertrophy with a dilated left atrium.
- Cardiac MRI confirmed prominent apical hypertrophy with near obliteration of the apical cavity.
Findings:
- This is a unique case of ApHCM presenting 17 years after heart transplantation in a patient on immunosuppressive therapy.
- ApHCM in transplanted patients on chronic immunosuppression is not well-described, raising questions about potential increased risk.
Implications:
- The study underscores the importance of considering ApHCM in heart transplant recipients, even years after transplantation.
- Further research is needed to understand the specific risks and long-term prognosis of ApHCM in this patient population.
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