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Published on: May 9, 2025
Correction to: Ceramicines M-P from Chisocheton ceramicus: isolation and structure-activity relationship study.
Alfarius Eko Nugroho1, Akiyo Hashimoto1, Chin-Piow Wong1
1Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo, 142-8501, Japan.
Researchers isolated novel compounds, Ceramicines M-P, from Chisocheton ceramicus. Structure-activity relationship studies revealed their potential biological activities.
Area of Science:
- Natural Product Chemistry
- Organic Chemistry
- Pharmacognosy
Context:
- Chisocheton ceramicus is a plant species known for its potential chemical constituents.
- Natural products serve as a foundation for drug discovery and development.
Purpose:
- To isolate and elucidate the structures of new compounds from Chisocheton ceramicus.
- To investigate the structure-activity relationships (SAR) of the isolated compounds.
Summary:
- Five new ceramicine compounds, Ceramicines M-P, were isolated from the bark of Chisocheton ceramicus.
- Their chemical structures were determined using spectroscopic methods.
- Preliminary SAR studies were conducted to understand their biological relevance.
Impact:
- Identification of novel chemical entities with potential pharmacological applications.
- Contribution to the understanding of the chemical diversity within the Chisocheton genus.
- Provides a basis for further investigation into the therapeutic potential of ceramicines.
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