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Bioimpedance analysis in detecting vascular diseases using blood pooling method
Yomna H Shash1, Mohamed A A Eldosoky1, Mohamed T Elwakad1
1a Department of Biomedical Engineering , Helwan University , Cairo , Egypt.
Insights
This study introduces a novel bioimpedance analysis (BIA) method combined with blood pooling to detect vascular diseases. The technique measures changes in blood vessel properties, enabling early identification of abnormalities.
Area of Science:
- Biomedical Engineering
- Cardiovascular Physiology
- Medical Imaging
Background:
- Cardiovascular diseases pose significant health risks.
- Blood vessel disorders can lead to severe or fatal health problems.
- Bioimpedance analysis (BIA) is a non-invasive technique for disease detection.
Purpose of the Study:
- To propose a novel scheme for extracting blood vessel properties using BIA and blood pooling.
- To detect vascular diseases by analyzing changes in bioimpedance measurements.
- To develop a mathematical model for vessel compliance and its effect on bioimpedance.
Main Methods:
- A novel scheme combining BIA with blood pooling to measure bioimpedance changes.
- Development of a mathematical model for vessel compliance.
- Construction of a finite element model of the human forearm for simulation.
- Simulation of various vascular disorders and impedance measurements before and after blood pooling.
Main Results:
- The proposed method successfully extracts blood vessel properties like compliance.
- Simulation results demonstrate BIA's ability to estimate vascular abnormalities.
- Changes in vessel compliance due to diseases are reflected in bioimpedance measurements.
Conclusions:
- The novel BIA and blood pooling method shows promise for detecting vascular diseases.
- Assessing changes in vessel compliance via bioimpedance is a viable approach for diagnosing vascular abnormalities.
- This technique offers a non-invasive, low-cost method for cardiovascular health assessment.
Abstract:
The cardiovascular system consists of the heart, a network of vessels and blood. Blood vessels are the tubular structure carrying blood through the tissues and organs. Disorders in this vast network can cause a range of health problems which can be severe or fatal. Blood pooling method has been used to measure the change in blood volume of the thigh, abdomen, limbs, etc. with the pressure change. This method occludes the vessel to prevent blood flowing out of the segment being investigated. In recent years, bioimpedance analysis (BIA) has become a popular modality in detecting various body diseases since it is a non-invasive, low-cost and simple for usage. In this paper, a novel scheme is proposed to extract the properties of a blood vessel (e.g. compliance) from which vascular diseases can be detected by analyzing the difference in bioimpedance measurements calculated before and after blood pooling. The paper presents a simple mathematical model to describe vessel compliance and its influence on bioimpedance measurements. Furthermore, the finite element model of human forearm is constructed, in which various vascular disorders are simulated and the impedances are measured before and after blood pooling. The simulation results clarify the ability of BIA in estimating vascular abnormalities, depending on the changes caused by diseases in vessel compliance, which are reflected on bioimpedance measurements using blood pooling method.
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