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Updated: Jan 26, 2026

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
Published on: February 28, 2021
Abstract:
In this issue, we begin our year-long focus on effective primary care systems, opening up critical lines of questioning around a fundamental issue: evaluation. How do we know whether a primary care system is making the grade, getting stronger or falling short? If we build it, what should it yield? There are myriad ways and measures to assess the quality, performance and outcomes of primary care systems (and ample arguments about which are best). What standards should primary care systems meet? What bars should be set, at what height, and to what end? What knowledge, skills and data are required ߝ and available ߝ to evaluate primary care models? Are evaluation results driving primary care quality improvement (QI) big and small?

