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Updated: Aug 12, 2026

Recording Light-evoked Postsynaptic Responses in Neurons in Dark-adapted, Mouse Retinal Slice Preparations Using Patch Clamp Techniques
Published on: February 11, 2015
Taming the "Black Dog" by Light: A Retina-Habenula Circuit Mechanism Unveiled
1Center for Neuroscience and Department of Psychiatry of First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China; Interdisciplinary Institute of Neuroscience and Technology, Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou 310058, China; NHC and CAMS Key Laboratory of Medical Neurobiology, Mental Health Center, Zhejiang University, Hangzhou 310058, China.
Abstract:
Light exerts powerful effects on mood and has been used for the therapeutic treatment of depression. In this issue of Neuron, Huang et al. (2019) identify a visual pathway linked to the lateral habenula mediating the antidepressant effects of light.

