Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Induced-fit Model01:13

Induced-fit Model

89.0K
Most chemical reactions in cells require enzymes—biological catalysts that speed up the reaction without being consumed or permanently changed. They reduce the activation energy needed to convert the reactants into products. Enzymes are proteins, that usually work by binding to a substrate—a reactant molecule that they act upon.
Enzymes exhibit substrate specificity, meaning that they can only bind to certain substrates. This is mainly determined by the shape and chemical...
89.0K
Vapor Pressure02:34

Vapor Pressure

40.2K
When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules move randomly about, they will occasionally collide with the surface of the condensed phase, and in some cases, these collisions will result in the molecules re-entering the condensed phase. The change from the gas phase to the liquid is called condensation. When the rate of condensation becomes equal to the rate of vaporization, neither the amount of the liquid nor the amount of the vapor...
40.2K
Increased Body Temperature01:25

Increased Body Temperature

6.5K
A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
6.5K
Increased pulse rate01:17

Increased pulse rate

1.1K
Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
1.1K
Definition and Measurement of Pressure: Atmospheric Pressure, Barometer, and Manometer02:57

Definition and Measurement of Pressure: Atmospheric Pressure, Barometer, and Manometer

42.8K
Gas pressure is caused by force exerted by gas molecules colliding with the surfaces of objects. Although the force of each collision is very small, any surface of an appreciable area experiences a large number of collisions in a short time, which can result in high pressure.
42.8K
Osmosis and Osmotic Pressure of Solutions02:40

Osmosis and Osmotic Pressure of Solutions

46.3K
A number of natural and synthetic materials exhibit selective permeation, meaning that only molecules or ions of a certain size, shape, polarity, charge, and so forth, are capable of passing through (permeating) the material. Biological cell membranes provide elegant examples of selective permeation in nature, while dialysis tubing used to remove metabolic wastes from blood is a more simplistic technological example. Regardless of how they may be fabricated, these materials are generally...
46.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comprehensive Epigenetic Landscape of Sulfur Mustard (SM) Exposure in HaCaT Keratinocytes.

Chemico-biological interactions·2026
Same author

Dietary fermented soybean meal in swine nutrition and effects on regulation of gut health, immune system and environment: a review.

Journal of animal science and technology·2026
Same author

Anesthesia for tracheoplasty in a patient with tracheal stenosis: a case report.

BMC anesthesiology·2026
Same author

Effects of Negative Meta-Stereotype on the Doctor-Patient Relationship: The Role of Imagined Intergroup Contact.

Behavioral sciences (Basel, Switzerland)·2026
Same author

The Biological Actions and Regulations of Lactic Acid-Linked Histone Lactylation.

Biology·2026
Same author

Practical exploration of real-time visual interactive artificial intelligence technology in cytopathology education.

Cancer cytopathology·2026

Related Experiment Video

Updated: Jan 26, 2026

Blast Quantification Using Hopkinson Pressure Bars
09:41

Blast Quantification Using Hopkinson Pressure Bars

Published on: July 5, 2016

9.4K

Blast Exposure Induces Ocular Functional Changes with Increasing Blast Over-pressures in a Rat Model.

Yanli Zhu1, Jeffrey T Howard1, Peter R Edsall2

  • 1a Ocular Trauma Division , Staff Scientist US Army Institute of Surgical Research, Joint Base San Antonio, USA.

Current Eye Research
|April 6, 2019
PubMed
Summary

Blast exposure can cause acute and chronic visual dysfunction. High-level blasts led to temporary vision problems and elevated intraocular pressure (IOP), with some lasting effects suggesting chronic retinal dysfunction.

Keywords:
Blastdysfunctionelectroretinographyocularoverpressure

More Related Videos

Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice
06:00

Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice

Published on: May 24, 2024

1.3K
Author Spotlight: Development of an Automated Camera-Based System for Real-Time Blast Overpressure Monitoring and TBI Risk Assessment in Military Training
06:20

Author Spotlight: Development of an Automated Camera-Based System for Real-Time Blast Overpressure Monitoring and TBI Risk Assessment in Military Training

Published on: December 6, 2024

3.3K

Related Experiment Videos

Last Updated: Jan 26, 2026

Blast Quantification Using Hopkinson Pressure Bars
09:41

Blast Quantification Using Hopkinson Pressure Bars

Published on: July 5, 2016

9.4K
Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice
06:00

Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice

Published on: May 24, 2024

1.3K
Author Spotlight: Development of an Automated Camera-Based System for Real-Time Blast Overpressure Monitoring and TBI Risk Assessment in Military Training
06:20

Author Spotlight: Development of an Automated Camera-Based System for Real-Time Blast Overpressure Monitoring and TBI Risk Assessment in Military Training

Published on: December 6, 2024

3.3K

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Trauma Research

Background:

  • Blast-related injuries pose a significant risk for acute and chronic visual dysfunction.
  • The long-term visual consequences and progression following blast exposure are not well understood.

Purpose of the Study:

  • To analyze ocular functional responses to varying blast exposure levels.
  • To identify a blast exposure threshold that causes acute and chronic visual dysfunction.

Main Methods:

  • Adult male Long-Evans rats were subjected to single-blast exposures at 78, 117, 164, or 213 kPa.
  • Ocular assessments included clinical eye exams, intraocular pressure (IOP) measurements, flash electroretinography (fERG), and spectral-domain optical coherence tomography (SD-OCT).

Main Results:

  • No fERG abnormalities were noted at 78 or 117 kPa.
  • A 164 kPa blast caused transient fERG deficits and minor IOP fluctuations.
  • The 213 kPa blast resulted in significant, temporary IOP elevation and bimodal fERG deficits, with a late-onset depression indicating chronic retinal dysfunction.

Conclusions:

  • Single blast exposure can induce acute and chronic fERG deficits and traumatic IOP elevation.
  • Noninvasive functional tests are promising for identifying individuals at risk for chronic visual deficits.
  • These tests may aid in early clinical diagnosis, rehabilitation, and treatment planning for blast-injured individuals.