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Updated: Jan 26, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Using the knowledge translation framework to change practical care of central catheters in a Brazilian neonatal unit
Gabriela Ramos Ferreira Curan1, Edilaine Giovanini Rossetto2, Thaíla Corrêa Castral3
1State University of Londrina, Londrina, Brazil. gabi_ramosf@hotmail.com.
Insights
Implementing central line bundles in a neonatal unit improved catheter maintenance practices significantly. This study highlights the impact of knowledge translation frameworks on healthcare quality and staff involvement in patient safety initiatives.
Area of Science:
- Neonatal Intensive Care
- Infection Prevention
- Healthcare Quality Improvement
Background:
- Central catheters are vital in intensive care but increase bloodstream infection risk.
- A knowledge-practice gap exists in optimal care for patients with central catheters.
- This study addresses this gap by implementing and evaluating central line bundles in a neonatal unit.
Purpose of the Study:
- To describe the implementation of central line bundles using a knowledge translation (KT) framework.
- To assess the impact of these bundles on care practices in a neonatal unit.
- To detail the implementation process in a Brazilian neonatal care setting.
Main Methods:
- A time-series quasi-experimental study design was employed.
- 289 non-participant observations of professional practices were conducted before and after bundle implementation.
- The study was conducted in a Brazilian neonatal unit.
Main Results:
- Bundle implementation focused on KT evidence, context, and facilitation.
- Catheter maintenance practices showed significant improvement (7/11 practices, p < 0.01).
- Catheter insertion practices had high initial adherence and satisfactory post-implementation results.
Conclusions:
- This is the first Brazilian study to use a KT framework for central line bundle implementation and evaluation in neonates.
- The study details the implementation process, emphasizing accountability and staff involvement.
- Effective implementation strategies are crucial for improving patient care and reducing infections.
Introduction:
The use of central catheters in intensive care is essential, but exposes the patient to the risk of a bloodstream infection. Although there is evidence to improve the care for these patients, there is a gap between knowledge and healthcare practices. This study was designed to describe the bundle implementation for central catheters in light of the knowledge translation (KT) conceptual framework in a neonatal unit and assess its impact on care practices with catheters.
Methodology:
A time-series quasi-experimental study design was conducted in a Brazilian neonatal unit, through 289 non-participant observations of professional practices before and after the implementation of the bundles.
Results:
The deployment of two bundles was guided through the steps of a careful selection of adopting KT evidence and context-related and investment factors in the facilitation process. The implementation of the bundles was planned by a group manager, mediated by a facilitator, and guided by targets established by professionals. The biggest impact was on the maintenance of catheters; seven of eleven practices improved significantly (p < 0.01). The insertion of catheters showed lesser impact of change, with high adequacy ratios before implementation, but also presented satisfactory adherence to recommendations.
Conclusions:
This is the first Brazilian study using the KT conceptual framework to develop, implement, and evaluate the impact of central line bundles in a neonatal care environment, detailing the implementation process. It highlights the importance of accountability and staff involvement in all stages of the study.
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