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Updated: Jan 26, 2026

Author Spotlight: Exploring Peripheral Mechanisms of Neuropathic Pain in Trigeminal Nerve Injury
Published on: February 9, 2024
Effect of peripheral cryoneurotomy and nerve transection on the trigeminal ganglion in rats
R D'Rozario1, K Ito2, A N Goss2
1Oral & Maxillofacial Surgery Unit, Royal Adelaide Hospital, The University of Adelaide, Adelaide, Australia; 33 Thames St., West Woolongong, NSW 2500, Australia.
Abstract:
In this experimental study, we did peripheral neurectomyand peripheral cryoneurotomy of the mental nerve in rats and histologically assessed their effects on the trigeminal ganglion at timed intervals for six months. There were marked irreversible changes in the neurectomy group whereas the cryoneurotomy group made a full recovery. These results help to explain the differing effects of these procedures on trigeminal neuralgia.
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