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Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...
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The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap junctions. These junctions comprise a few hundred to thousands of molecular channels, each made of two halves, called the connexon hemichannel. A connexon is a hexamer of six transmembrane connexin proteins, which assemble radially, thus forming a pore or channel in the center. One connexon hemichannel docks with a corresponding connexon on the...
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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
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Principles of Rodent Surgery for the New Surgeon
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Surgery at Sea: Exploring the Training Gap for Isolated Military Surgeons.

Matthew D Nealeigh1, Walter B Kucera1, Matthew J Bradley1

  • 1Department of Surgery at the Uniformed Services University, the Walter Reed National Military Medical Center, Bethesda, Maryland.

Journal of Surgical Education
|April 7, 2019
PubMed
Summary

Military surgeons face isolated surgical care at sea. Training provides general skills but lacks exposure to rare, deployment-specific cases, impacting readiness for isolated roles.

Keywords:
Isolated surgeonMedical KnowledgePatient CarePractice-Based Learning and Improvementmilitarysurgery residentsurgical education

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Area of Science:

  • Military Medicine
  • Surgical Education
  • Naval Operations

Background:

  • Newly-graduated military general surgeons often serve as the sole surgical provider on naval vessels.
  • This isolated role demands broad surgical capability, irrespective of specialized training.
  • Assessing preparedness for this unique operational environment is crucial.

Purpose of the Study:

  • To analyze trends in surgical procedures performed at sea over 25 years.
  • To evaluate the preparedness of military surgical trainees for isolated afloat roles.
  • To identify gaps in surgical skills and knowledge for deployed environments.

Main Methods:

  • Reviewed deidentified US Navy Ship's Surgeon case logs (1990s-2017) for case load trends in 5 key categories.
  • Mapped procedures to American College of Surgeons/Military Health System Knowledge, Skills, and Attitudes (KSAs).
  • Compared recent military resident case logs with afloat cases to assess trainee experience.

Main Results:

  • Analysis of 1340 surgeries revealed 74% correlated to intraoperative KSAs; vasectomy was most common (23%).
  • Case volume per deployment significantly declined overall (p < 0.001).
  • Resident training showed limited experience in urologic/gynecologic, orthopedic, and open appendectomy procedures.

Conclusions:

  • A formal repository for afloat surgery data is lacking, hindering analysis.
  • Current surgical education offers broad training but insufficient exposure to rare, deployment-specific cases.
  • Investment in targeted training is needed to ensure competency for isolated, afloat surgeons.