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Factors Associated with Delayed Transition to Oral Feeding in Infants with Single Ventricle Physiology
Joshua D Kurtz1, Shahryar M Chowdhury1, Francis K Woodard1
1Department of Pediatrics, Division of Pediatric Cardiology, Medical University of South Carolina, Charleston, SC.
Insights
Infants with single ventricle physiology often require prolonged gastrostomy tube dependence. Preoperative oral feeding is a key factor in achieving earlier transition to exclusive oral feeding, potentially reducing dependence.
Area of Science:
- Pediatric Cardiology
- Neonatology
- Gastroenterology
Background:
- Infants with single ventricle physiology present unique feeding challenges.
- Prolonged gastrostomy tube dependence impacts infant development and family well-being.
Purpose of the Study:
- To determine the time to exclusive oral feeding in infants with single ventricle physiology.
- To identify risk factors for extended gastrostomy tube use in this population.
Main Methods:
- Retrospective analysis of 78 infants with single ventricle physiology.
- Categorization of oral feeding transition into early, mid, and late groups.
- Statistical analysis to identify factors associated with feeding transition.
Main Results:
- 59% of infants were discharged with a gastrostomy tube.
- 50% achieved early transition to oral feeding.
- Preoperative oral feeding, higher weight-for-age z-scores, and shorter intensive care unit/hospital stays were associated with early transition.
Conclusions:
- Preoperative oral feeding is a significant factor in achieving timely oral feeding transition.
- Early identification of feeding difficulties and interventions may improve outcomes.
Objectives:
To describe the duration of time to achieve exclusive oral feeding in infants with single ventricle physiology and to identify risk factors associated with prolonged gastrostomy tube dependence.
Study Design:
Single center, retrospective study of infants with single ventricle physiology. The primary outcome was duration of time required to achieve oral feeding. Transition periods were defined as exclusive oral feeding by Glenn palliation (early), by 1 year of age (mid), or after 1 year of age (late).
Results:
Seventy-eight infants were analyzed; 46 (59%) were discharged to home with a gastrostomy tube after the initial hospitalization. Overall, 39 infants (50%) achieved early transition, 14 (18%) mid, and 18 (23%) late. The group who achieved early transition had a higher percentage of preoperative oral feeding (P < .01), greater weight-for-age z score at initial discharge (P = .03), shorter initial intensive care unit duration (P < .01), shorter initial hospital length of stay (P < .01), and greater weight-for-age z score at Glenn admission (P = .02). No preoperative oral feeding (OR = 0.12, P = .02) and greater number of cardiac medications at initial discharge (OR = 3.8, P = .03) were associated with failure to achieve early transition. No preoperative oral feeding (OR = 0.09, P = .01) and longer initial intensive care unit duration (OR = 1.1, P = .03) were associated with failure to achieve mid transition.
Conclusion:
Preoperative oral feeding may potentially be a modifiable factor to help improve early transition to oral feeding.
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