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Updated: Jan 26, 2026

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
Published on: August 5, 2021
Apoptotic cell-derived extracellular vesicles: structure-function relationships
Lois R Grant1, Ivana Milic1, Andrew Devitt2
1School of Life and Health Sciences, Aston Research Centre for Healthy Ageing, Aston University, Birmingham, U.K.
Abstract:
Apoptosis is an essential process for normal physiology and plays a key role in the resolution of inflammation. Clearance of apoptotic cells (ACs) involves complex signalling between phagocytic cells, ACs, and the extracellular vesicles (EVs) they produce. Here, we discuss apoptotic cell-derived extracellular vesicles (ACdEVs) and how their structure relates to their function in AC clearance and the control of inflammation, focussing on the ACdEV proteome. We review the current knowledge, ongoing work and future directions for research in this field.
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