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Updated: Jan 26, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Obsessive Compulsive Disorder: A Pathology of Self-Confidence?
Julian Kiverstein1, Erik Rietveld2, Heleen A Slagter3
1Academic Medical Centre, Department of Psychiatry, University of Amsterdam, Amsterdam, The Netherlands; Institute of Logic, Language and Computation, University of Amsterdam, Amsterdam, The Netherlands.
Abstract:
A striking change OCD patients repeatedly describe following treatment with deep brain stimulation (DBS) of the ventral anterior limb of internal capsule (vALIC) is an immediate increase in self-confidence. We show how the DBS-induced changes in self-confidence reported by our patients can be understood neurocognitively in terms of active inference.
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