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Recent advances in the management of diabetic retinopathy

Nabeela Dulull1, Faith Kwa2, Narin Osman3

  • 1Discipline of Pharmacy, School Health and Biomedical Sciences, RMIT University, Bundoora, VIC3083, Australia.

Drug Discovery Today
|April 8, 2019
PubMed

Insights

Diabetic retinopathy (DR) is a leading cause of vision loss. New treatments are needed to target early stages and slow progression, requiring identification of novel therapeutic targets and accurate disease models.

Area of Science:

  • Ophthalmology
  • Endocrinology
  • Vascular Biology

Background:

  • Diabetic retinopathy (DR) is a significant microvascular complication of diabetes.
  • It is the primary cause of vision loss among diabetic individuals.
  • Current treatments are insufficient for early-stage disease or halting progression.

Purpose of the Study:

  • To review the pathological mechanisms of diabetic retinopathy development.
  • To highlight recent advances in current and emerging treatments for DR.
  • To emphasize the need for new therapeutic targets and accurate disease models.

Main Methods:

  • Literature review of pathological mechanisms in DR.
  • Analysis of current therapeutic strategies for DR.
  • Exploration of emerging treatments and research directions for DR.

Main Results:

  • Detailed overview of the pathological pathways contributing to DR.
  • Summary of established treatments and their limitations.
  • Identification of promising novel therapeutic targets and approaches.

Conclusions:

  • Effective management of diabetic retinopathy requires targeting early disease stages.
  • Further research into novel therapies and accurate disease models is crucial.
  • Advancements in understanding DR pathology are paving the way for improved treatments.

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