Related Experiment Video

Updated: Jan 26, 2026

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders
05:58

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders

Published on: February 3, 2021

4.2K

Diagnosis of Invasive Fungal Infections in Children

Rachna Seth1, Immaculata Xess2, Manisha Jana3

  • 1Department of Pediatrics, AIIMS, New Delhi, India. Correspondence to: Dr Rachna Seth, Professor, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India. drrachnaseth@yahoo.co.in.

Indian Pediatrics
|April 8, 2019
PubMed

Insights

Invasive fungal infections are challenging to diagnose due to vague symptoms and testing difficulties. This review covers their definition, profiles, and diagnostic methods to improve patient outcomes.

Area of Science:

  • Medical Mycology
  • Infectious Diseases

Background:

  • Invasive fungal infections (IFIs) are significant causes of illness and death, especially in vulnerable populations.
  • Diagnosis is complicated by non-specific signs and symptoms, hindering early detection.
  • Challenges in sample collection and limited data on fungal biomarkers impede timely diagnosis.

Purpose of the Study:

  • To review the definition, clinical and microbial characteristics, and diagnostic approaches for invasive fungal infections.
  • To highlight the difficulties in recognizing and diagnosing IFIs.
  • To provide a comprehensive overview for healthcare professionals.

Main Methods:

  • Literature review focusing on invasive fungal infections.
  • Analysis of clinical and microbiological data related to IFIs.
  • Examination of current and emerging diagnostic modalities for fungal infections.

Main Results:

  • IFIs present with non-specific symptoms, making early recognition difficult.
  • Diagnostic challenges include sample acquisition and interpretation of biomarker data.
  • Delayed diagnosis leads to empirical antifungal use and resistance.

Conclusions:

  • Accurate and timely diagnosis of IFIs is crucial for effective treatment.
  • Further research into fungal biomarkers and molecular diagnostics is needed.
  • Improved diagnostic strategies can reduce morbidity, mortality, and antifungal resistance.

More Related Videos

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

2.9K
Engineering Chimeric Antigen Receptor-Natural Killer Cells Targeting Fungal Infections Using the Non-viral Sleeping Beauty Transposon System08:29

Engineering Chimeric Antigen Receptor-Natural Killer Cells Targeting Fungal Infections Using the Non-viral Sleeping Beauty Transposon System

Published on: October 4, 2024

1.3K

Related Concept Videos

Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
1.1K
Nursing Diagnosis01:22

Nursing Diagnosis

Following assessment, a nursing diagnosis is the next step in the nursing process. It begins after the nurse has collected and recorded the patient data. The purpose of diagnosing is to identify how the client responds to actual or potential health processes, identify factors that bestow or that cause health problems, the etiologies, and identify resources or strengths the individual, group, or community can draw on to prevent or resolve problems.
The nursing diagnosis focuses on evidence-based...
3.8K
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
480
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
1.1K
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
932
Documentation of Nursing Diagnosis01:10

Documentation of Nursing Diagnosis

The nurse documents nursing diagnoses and enters them into the patient record. The identified patient's nursing diagnosis is either written out with a plan of care or entered into the electronic health record.
In some settings, data-driven computerized decision support systems are in place, allowing for more accurate nursing diagnoses. The database within one of these systems includes diagnostic labels defining characteristics, activities, and indicators for nursing. A nurse enters...
1.7K