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A Case of Polymyalgia Rheumatica Following Robotic-Assisted Radical Prostatectomy for High-Grade Prostate Cancer

Madeleine S Deming1

  • 1Internal Medicine Consult Service, Clinical Center, National Institutes of Health (NIH), Bethesda, MD, USA.

The American Journal of Case Reports
|April 8, 2019
PubMed

Insights

Polymyalgia rheumatica (PMR) can occur after prostate surgery. This case report details PMR developing post-robotic prostatectomy, highlighting a potential link between prostate cancer treatment and this rheumatic condition.

Area of Science:

  • Rheumatology
  • Urology
  • Oncology

Background:

  • Polymyalgia rheumatica (PMR) is a common inflammatory condition affecting individuals over 50.
  • The exact triggers for PMR remain unclear, though associations with other conditions have been noted.
  • Previous reports suggest a link between prostate cancer and PMR, including cases preceding or following treatment.

Observation:

  • A 61-year-old male developed bilateral groin, thigh, and shoulder pain two weeks after robotic-assisted radical prostatectomy for high-grade prostate adenocarcinoma.
  • Elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels were observed.
  • Symptoms significantly improved (90%) within four weeks of initiating tapered methylprednisolone treatment.

Findings:

  • This report presents a case of PMR occurring after robotic-assisted prostatectomy.
  • This is the second reported instance of PMR following any prostatectomy and the first following a robotic-assisted procedure.
  • The findings suggest a potential temporal association between prostatectomy and the onset of PMR.

Implications:

  • The case highlights a possible, though not fully understood, connection between prostate cancer surgery and the development of PMR.
  • Further research is warranted to explore the underlying mechanisms and confirm this association.
  • Clinicians should consider PMR in patients presenting with relevant symptoms post-prostatectomy.

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