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Related Concept Videos

Lung Capacity01:47

Lung Capacity

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The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
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Pleura of the Lungs01:13

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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Gross Anatomy of the Lungs01:17

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The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
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Cancer02:18

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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What is Cancer?02:12

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Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
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Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
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Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

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Lung Cancer.

Faria Nasim1, Bruce F Sabath1, George A Eapen1

  • 1Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Unit 1462, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

The Medical Clinics of North America
|April 9, 2019
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Summary
This summary is machine-generated.

Lung cancer screening with low-dose computed tomography reduces mortality. This review outlines lung cancer diagnosis, staging, and personalized treatment options for clinicians to better guide patients.

Keywords:
ChemotherapyLung cancerScreeningSmokingStaging

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Area of Science:

  • Oncology
  • Pulmonology
  • Radiology

Background:

  • Lung cancer remains the leading cause of cancer-related mortality globally.
  • Early detection through low-dose computed tomography (LDCT) screening significantly improves survival rates.
  • Advances in personalized medicine have revolutionized lung cancer treatment strategies.

Purpose of the Study:

  • To provide a comprehensive overview of lung cancer.
  • To assist clinicians in identifying at-risk patients.
  • To familiarize healthcare providers with current lung cancer care options.

Main Methods:

  • Review of current literature on lung cancer screening, diagnosis, staging, and treatment.
  • Synthesis of information on diagnostic modalities and therapeutic approaches.
  • Focus on personalized therapies and patient management.

Main Results:

  • LDCT screening is an effective tool for reducing lung cancer mortality.
  • Diagnosis and staging involve multiple modalities.
  • Personalized therapies offer improved outcomes for specific lung cancer subtypes.

Conclusions:

  • Effective management of lung cancer requires a multidisciplinary approach.
  • Clinicians need to be updated on the latest diagnostic and therapeutic advancements.
  • Guiding patients through their lung cancer journey necessitates comprehensive knowledge of the disease and its care options.