Current status and future perspective of structural heart disease intervention
Noriaki Tabata1, Jan-Malte Sinning2, Koichi Kaikita3
1Heart Center Bonn, Department of Medicine II, University Hospital Bonn, Germany; Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Journal of Cardiology
|April 9, 2019
Summary
Transcatheter aortic valve implantation (TAVI) and other structural heart disease interventions are increasingly used for valvular heart disease, improving outcomes for many patients. Further research and device development will expand these minimally invasive treatment options.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Valvular heart diseases frequently lead to heart failure, with severe conditions worsening clinical outcomes.
- Degenerative aortic and mitral valve diseases, along with tricuspid valve dysfunction, significantly impact patient prognosis.
Purpose of the Study:
- To review the advancements and expanding role of minimally invasive structural heart disease (SHD) interventions.
- To discuss the current status and future potential of transcatheter therapies for valvular heart diseases.
Main Methods:
- Review of current literature and clinical data on transcatheter aortic valve implantation (TAVI) and other structural heart interventions.
- Analysis of the evolution of TAVI indications and emerging transcatheter technologies for mitral and tricuspid valve diseases.
Main Results:
- Transcatheter aortic valve implantation (TAVI) is a disruptive technology for severe aortic stenosis, with next-generation devices minimizing complications.
- Indications for TAVI are expanding to lower-risk patients and complex anatomies.
- Growing interest in transcatheter solutions for mitral regurgitation (MR) and tricuspid regurgitation (TR) is evident.
Conclusions:
- Minimally invasive SHD interventions have significantly improved quality of life and survival for patients previously ineligible for surgery.
- Continued technical and device advancements, alongside accumulating evidence, will broaden the scope and future applications of SHD interventions.
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