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Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties

Xiangqian Kong1, Jie Chen2, Wenbing Xie1

  • 1The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Cancer Cell
|April 9, 2019
PubMed
Abstract

Keywords:
UHRF1colorectal cancer prognosisdomain functionsmaintenance DNA methylationnext-generation DNA demethylating agentsoncogenic propertiestumor suppressor gene silencing

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