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Related Concept Videos

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

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Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
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Node Analysis for AC Circuits01:14

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Consider an angioplasty system featuring a catheter equipped with a turbine, a critical tool for removing plaque deposits from coronary arteries. This intricate medical device operates using a circuit model reminiscent of a dual-node RLC circuit powered by a current-controlled voltage source.
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Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
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Atomic Orbitals02:44

Atomic Orbitals

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An atomic orbital represents the three-dimensional regions in an atom where an electron has the highest probability to reside. The radial distribution function indicates the total probability of finding an electron within the thin shell at a distance r from the nucleus. The atomic orbitals have distinct shapes which are determined by l, the angular momentum quantum number. The orbitals are often drawn with a boundary surface, enclosing densest regions of the cloud.
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Protein Networks02:26

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An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
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Anatomy of the Heart01:27

Anatomy of the Heart

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The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
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Related Experiment Video

Updated: Jan 26, 2026

High-resolution Optical Mapping of the Mouse Sino-atrial Node
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Pheochromocytoma and sinus node dysfunction.

Mary Lee1, Dane Langsjeon2, Srikala Devabhaktuni2

  • 1Department of Internal Medicine, Baylor Scott & White Medical Center-TempleTempleTexas.

Proceedings (Baylor University. Medical Center)
|April 9, 2019
PubMed
Summary

Pheochromocytomas, rare tumors causing varied symptoms, can lead to heart rhythm issues. Surgical removal of the tumor resolved sinus node dysfunction in a patient, highlighting a treatable cause of cardiac complications.

Keywords:
Catecholaminejunctional escape rhythmspheochromocytomasick sinus syndromesinus arrestsinus node dysfunction

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Related Experiment Videos

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Area of Science:

  • Endocrinology
  • Cardiology
  • Oncology

Background:

  • Pheochromocytomas are rare neuroendocrine tumors producing excess catecholamines.
  • Classic symptoms include hypertension, tachycardia, and headaches.
  • Cardiac complications like bradyarrhythmias are uncommon but significant.

Observation:

  • A case presented with pheochromocytoma leading to sinus pauses and junctional escape rhythms.
  • This atypical presentation of pheochromocytoma involved significant sinus node dysfunction.

Findings:

  • The patient experienced bradyarrhythmias, specifically sinus pauses and junctional escape rhythms.
  • Complete resolution of sinus node dysfunction was observed post-adrenalectomy.

Implications:

  • This case underscores the importance of considering pheochromocytoma in unexplained cardiac rhythm disturbances.
  • Surgical intervention (adrenalectomy) can effectively treat associated sinus node dysfunction.
  • Highlights the link between neuroendocrine tumors and cardiovascular complications.