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Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional

Jacqueline Le Geyt1,2, Stephanie Hauck3, Mark Lee2

  • 1Paediatric Emergency Department, Royal Alexandra Children's Hospital, Brighton, UK.

BMJ Paediatrics Open
|April 9, 2019
PubMed

Insights

This study found an 8.1% prevalence of respiratory syncytial virus (RSV) in Kenyan children hospitalized with acute respiratory infections (ARIs). RSV-positive infants were younger, indicating a need for targeted interventions for this vulnerable group.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Acute respiratory infections (ARIs) are a major global cause of death in children under five.
  • Previous studies on respiratory syncytial virus (RSV) prevalence in Kenya have shown inconsistent results.

Purpose of the Study:

  • To determine the prevalence of RSV infection among children admitted with ARI who meet WHO bronchiolitis criteria.
  • To compare RSV prevalence in Kenya with prior research.

Main Methods:

  • A prospective cross-sectional prevalence study was conducted.
  • Data was collected from 234 participants across five hospitals in central and highland Kenya between April and June 2015.

Main Results:

  • The overall RSV positive rate was 8.1%, which is lower than previously reported in Kenya.
  • Children with RSV infection were, on average, 5 months younger than those without RSV.

Conclusions:

  • The RSV prevalence in this cohort is lower than anticipated, suggesting potential shifts or regional variations.
  • Younger age is a significant factor in RSV-positive cases among hospitalized children with bronchiolitis in Kenya.

Keywords:
epidemiologyrespiratorytropical paediatrics

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