Atrial fibrillation, with ACS and PCI: walking a tightrope

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...

Direct current is a flow of electric charge in only one direction and has a steady state of constant voltage in the circuit. Rectifiers, batteries, commutator-equipped generators, and fuel cells are some examples of devices that generate direct current. Nowadays, most applications use a time-varying voltage source. Alternating current is a flow of electric charge that periodically reverses direction. An alternating current is produced by an alternating emf that is generated in a power plant. If...

An alternating emf or voltage source is needed to supply an alternating current (AC) to a circuit. A coil of wire rotating in a magnetic field at a constant angular speed represents such a source. It also generates a sinusoidal alternating emf and serves as an industrial alternator.
One-way current through the meter is measured using diodes. A diode is a device with better conductivity in one direction compared to the other; in its ideal state, it has zero resistance in one direction and allows...

In a DC circuit, the power consumed is simply the product of the DC voltage times the DC current, given in watts. However, the power consumed for AC circuits with reactive components is calculated differently. Since electrical power is the "rate" at which energy is used in a circuit, all electrical and electronic components and devices have a safe operating range for electrical power.
In a DC circuit, there is no sinusoidal waveform associated with the supply; the voltages and currents are...

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...