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Long-term outcomes of strabismus surgery in Mobius sequence
1a Departments of Ophthalmology and Visual Sciences and Pediatrics, St. Louis Children's Hospital, Washington University School of Medicine , St. Louis , MO.
Strabismus
|April 9, 2019
Summary
Bilateral medial rectus muscle recession effectively treats esotropia in Mobius sequence patients. This strabismus surgery offers good long-term stability and improved binocularity for affected children.
Area of Science:
- Ophthalmology
- Pediatric Neurology
- Craniofacial Disorders
Background:
- Mobius sequence is a rare neurological disorder affecting cranial nerves VI and VII.
- It causes facial weakness and impaired ocular abduction, often leading to esotropia.
Purpose of the Study:
- To evaluate the long-term outcomes of strabismus surgery in children with Mobius sequence.
- To assess the efficacy of surgical correction for esotropia in this patient population.
Main Methods:
- Retrospective analysis of five children with Mobius sequence who underwent strabismus surgery.
- Surgical procedures included bilateral medial rectus muscle recession, with some patients receiving inferior medial rectus transposition or vertical strabismus surgery.
- Long-term follow-up data were collected and analyzed.
Main Results:
- All patients had preoperative esotropia (20–30 PD) and limited abduction.
- Post-surgery, all patients achieved horizontal alignment <8 PD with some degree of binocularity.
- Follow-up ranged from 4 to 19.5 years, demonstrating sustained results.
Conclusions:
- Bilateral medial rectus muscle recession is a safe and effective treatment for esotropia in Mobius sequence.
- The surgical approach provides stable, long-term improvements in ocular alignment and binocular function.
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