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Published on: April 27, 2011
BK virus: Current understanding of pathogenicity and clinical disease in transplantation
Stephanie Chong1, Michelle Antoni2, Andrew Macdonald2
1Department of Renal Medicine, Royal Free Hospital, University College London, London, UK.
Abstract:
BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that continues to pose a significant challenge to clinicians due to its frequently unpredictable onset, persistence, and the lack of effective antiviral agents or prevention strategies. This review covers our current understanding of epidemiology, viral transmission and disease progression, and treatment and prevention strategies that have been used to manage this disease.
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