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Updated: Jan 26, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
Published on: April 9, 2014
HIV and HCV screening among trauma patients
Gina M Simoncini1, Josue Oyola-Jimenez1, Davone Singleton1
11 Department of Medicine, Section of General Internal Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Trauma patients screened for hepatitis C virus (HCV) and HIV showed high infection rates. A new program successfully linked many patients with HCV and HIV to essential care and treatment services.
Area of Science:
- Public Health
- Infectious Diseases
- Trauma Surgery
Background:
- Hepatitis C virus (HCV) and Human Immunodeficiency Virus (HIV) pose significant public health challenges.
- Trauma patients represent a vulnerable population with potential for undiagnosed infections.
- Integrating screening into trauma services can identify infections and facilitate care linkage.
Purpose of the Study:
- To establish and evaluate a screening program for HCV and HIV within a trauma surgery service.
- To assess the prevalence of HCV and HIV among trauma patients.
- To determine the effectiveness of linking diagnosed patients to care and treatment.
Main Methods:
- A screening program was implemented for trauma patients, offering HCV antibody and HIV testing.
- Demographic data, including intravenous drug use history, were collected.
- A dedicated navigator facilitated linkage to care and treatment services.
Main Results:
- 1160 trauma patients were screened; 162 (14%) tested positive for HCV antibodies, with 39.5% reporting a history of intravenous drug use.
- 46 (68.7%) HCV-positive patients were linked to care, and 55 (34%) engaged in treatment.
- 155 patients were screened for HIV, revealing 21 (13.5%) living with HIV (PLWH) and 2 (1.3%) new infections.
- All newly diagnosed PLWH were linked to care, with 73.7% on antiretroviral therapy.
Conclusions:
- The study demonstrates the feasibility and high yield of HCV and HIV screening in trauma patients.
- The integrated program achieved high rates of linkage to care for HCV and HIV positive individuals.
- Trauma surgery presents a critical opportunity to diagnose and manage viral infections in a high-risk population.
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