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Related Concept Videos

Gap Junctions01:37

Gap Junctions

57.0K
Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...
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Gap Junctions01:27

Gap Junctions

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The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap junctions. These junctions comprise a few hundred to thousands of molecular channels, each made of two halves, called the connexon hemichannel. A connexon is a hexamer of six transmembrane connexin proteins, which assemble radially, thus forming a pore or channel in the center. One connexon hemichannel docks with a corresponding connexon on the...
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Band Theory02:35

Band Theory

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When two or more atoms come together to form a molecule, their atomic orbitals combine and molecular orbitals of distinct energies result. In a solid, there are a large number of atoms, and therefore a large number of atomic orbitals that may be combined into molecular orbitals. These groups of molecular orbitals are so closely placed together to form continuous regions of energies, known as the bands.
The energy difference between these bands is known as the band gap.
Conductor, Semiconductor,...
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DNA-only Transposons02:57

DNA-only Transposons

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DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
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Interphase00:54

Interphase

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The cell cycle occurs over approximately 24 hours (in a typical human cell) and in two distinct stages: interphase, which includes three phases of the cell cycle (G1, S, and G2), and mitosis (M). During interphase, which takes up about 95 percent of the duration of the eukaryotic cell cycle, cells grow and replicate their DNA in preparation for mitosis.
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Contact-dependent Signaling01:19

Contact-dependent Signaling

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Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
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Recording Gap Junction Current from Xenopus Oocytes
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What Do We Know About the Stewardship Gap.

Jeremy York1, Myron Gutmann2, Francine Berman3

  • 1University of Michigan.

Data Science Journal
|April 10, 2019
PubMed
Summary
This summary is machine-generated.

Scholarly data stewardship faces multiple gaps, not just one. Understanding these interconnected gaps is crucial for improving data accessibility and responsible management in research.

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Area of Science:

  • Data Science
  • Information Science
  • Scholarly Communication

Background:

  • Digital data are integral to 21st-century innovation and decision-making.
  • A suspected gap exists between produced scholarly data and its effective stewardship and accessibility.
  • Limited understanding of data size, characteristics, and sustainability hinders progress.

Purpose of the Study:

  • To investigate the characteristics and measures of the stewardship gap in sponsored scholarly activity in the United States.
  • To define the scholarly data stewardship gap based on a literature review.
  • To identify areas where metrics and measurements exist and where they are needed.

Main Methods:

  • Literature review to establish a preliminary definition of the stewardship gap.
  • Analysis of existing metrics and measurements for various components of the stewardship gap.
  • Identification of areas requiring further research and measurement development.

Main Results:

  • The stewardship gap is multifaceted, comprising multiple interconnected "gaps."
  • Relationships between these gaps can inform strategies for data stewardship.
  • Current studies exhibit imbalances in the types and depth of investigations into the stewardship gap.

Conclusions:

  • Addressing the scholarly data stewardship gap requires a nuanced approach recognizing multiple contributing factors.
  • Strategic interventions can be developed by understanding the interdependencies between different stewardship gaps.
  • Further research is needed to develop comprehensive metrics and conduct in-depth studies across all facets of the stewardship gap.