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Updated: Jan 26, 2026

mirMachine: A One-Stop Shop for Plant miRNA Annotation
Published on: May 1, 2021
Computational Methods to Investigate the Impact of miRNAs on Pathways
Salvatore Alaimo1, Giovanni Micale1, Alessandro La Ferlita2
1Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Abstract:
Pathway analysis is a wide class of methods allowing to determine the alteration of functional processes in complex diseases. However, biological pathways are still partial, and knowledge coming from posttranscriptional regulators has started to be considered in a systematic way only recently. Here we will give a global and updated view of the main pathway and subpathway analysis methodologies, focusing on the improvements obtained through the recent introduction of microRNAs as regulatory elements in these frameworks.
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