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Updated: Jan 26, 2026

Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity
Published on: June 25, 2015
Mucosal vaccines and technology
A Miquel-Clopés1, E G Bentley2, J P Stewart2
1Gut Microbes and Health Research Programme, Quadram Institute Bioscience, Norwich, UK.
Abstract:
There is an urgent and unmet need to develop effective vaccines to reduce the global burden of infectious disease in both animals and humans, and in particular for the majority of pathogens that infect via mucosal sites. Here we summarise the impediments to developing mucosal vaccines and review the new and emerging technologies aimed at overcoming the lack of effective vaccine delivery systems that is the major obstacle to developing new mucosal vaccines.
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