Related Experiment Video
Updated: Jan 26, 2026
Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Incidence and prevalence of keratoconus in Denmark - an update
Sashia Bak-Nielsen1, Cecilia H Ramlau-Hansen2, Anders Ivarsen1
1Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.
Purpose:
To describe the annual incidence rate of keratoconus in Denmark 1995-2015 and prevalence of keratoconus in the National Danish Patient Register 1977-2015.
Methods:
All patients diagnosed with keratoconus in the National Danish Patient Register 1977-2015 were included in the study. The annual incidence rates and the overall prevalence of diagnosed keratoconus in the register were calculated using life tables from the general Danish population. A sub-analysis excluding immigrants and descendants was performed.
Results:
An increase in the annual incidence rate was seen from 1.24 per 100 000 person-years in 2003 to 3.83 per 100 000 in 2011. The average incidence rate 2011-2015 was 3.60 per 100 000 person-years. A survey of primary-sector ophthalmologists supported that the register data could be considered complete from 2011. The prevalence of diagnosed keratoconus in the National Patient Register 1977-2015 was 44 per 100 000 persons. Excluding immigrants and descendants yielded an average incidence rate 2011-2015 of 2.89 per 100 000 person-years and a prevalence of diagnosed keratoconus in the National Patient Register 1977-2015 of 40 per 100 000 persons.
Conclusion:
The present incidence rate (based on 2011-2015 data) has increased 2-3-fold during the last 10-15 years. The increase is possibly largely a consequence of more complete data due to the availability of corneal cross-linking, which has changed the referral pattern from the primary sector. Other factors such as better diagnostic tools and immigration may also play a role.
More Related Videos
06:49In situ Grazing Incidence Small Angle X-ray Scattering on Roll-To-Roll Coating of Organic Solar Cells with Laboratory X-ray Instrumentation
Published on: March 2, 2021
06:05Using Neutron Spin Echo Resolved Grazing Incidence Scattering to Investigate Organic Solar Cell Materials
Published on: January 15, 2014
Related Concept Videos
01:08Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
01:21Types of Reports II: Incident or Occurrence Report
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
01:42Schemas
01:26What is an Electrochemical Gradient?
The chemical gradient relies on differences in the abundance of a substance on the outside versus the inside of a cell and flows from areas of high to low ion concentration. In contrast, the electrical gradient revolves around an...
02:16Measures of Central Tendency
02:59The Nernst Equation
The interconnection between standard cell potentials and various thermodynamic parameters such as the standard free energy change ΔG° and equilibrium constant K has been previously explored. For example, a redox reaction involving zinc(II) and tin(II) ions at 1 M concentration with Eºcell = +0.291 V and ΔG° = −56.2 kJ is spontaneous.