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Published on: November 27, 2019
Web-Based Multidomain Lifestyle Programs for Brain Health: Comprehensive Overview and Meta-Analysis
Linda Mp Wesselman1, Astrid M Hooghiemstra1,2, Linda J Schoonmade3
1Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
Web-based multidomain lifestyle programs show potential for improving brain health and preventing dementia. These interventions, focusing on physical and cognitive activities, offer a promising scalable approach to cognitive decline management.
Area of Science:
- Neuroscience
- Public Health
- Digital Health
Background:
- Global dementia cases are rising due to population aging.
- Pharmaceutical interventions for cognitive decline are lacking.
- Lifestyle factors, like physical and cognitive activity, influence dementia risk, making multidomain interventions promising.
Purpose of the Study:
- To overview Web-based multidomain lifestyle programs for brain health in healthy adults.
- To describe program characteristics, availability, and user experience.
- To meta-analyze program effectiveness on brain health outcomes.
Main Methods:
- Searched PubMed, EMBASE, PsycINFO for Web-based lifestyle programs.
- Included programs targeting brain health, multiple lifestyle factors, and healthy adults.
- Conducted a meta-analysis on effectiveness using controlled studies.
Main Results:
- Identified 14 Web-based multidomain lifestyle programs; all targeted physical and cognitive activities.
- Only 29% of programs were publicly available and free.
- Meta-analysis of 3 studies showed a small-to-medium positive effect on brain health outcomes (SMD=0.45).
Conclusions:
- 14 Web-based multidomain lifestyle programs for brain health were identified.
- Programs varied in characteristics and evaluation methods.
- These interventions show potential for dementia prevention and improving brain health outcomes.
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