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Related Concept Videos

ATP Driven Pumps II: P-type Pumps01:34

ATP Driven Pumps II: P-type Pumps

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The P-type pumps are a large family of integral membrane transporter ATPases. They are divided into five major types based on substrate specificity, from I to V.
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
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ATP Driven Pumps III: V-type Pumps01:30

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V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
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ATP Driven Pumps I: An Overview01:27

ATP Driven Pumps I: An Overview

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ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
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Tracheostomy Suctioning II: Procedure01:23

Tracheostomy Suctioning II: Procedure

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Tracheostomy suctioning is a vital nursing procedure that involves removing secretions from the tracheostomy tube to maintain airway patency and prevent respiratory complications. Nurses need to understand the proper technique for tracheostomy suctioning to ensure patient safety and comfort. In this guide, we will outline the step-by-step process for performing tracheostomy suctioning, including preparing the sterile field, donning personal protective equipment (PPE), lubricating and connecting...
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Suctioning the Oropharyngeal Airway01:25

Suctioning the Oropharyngeal Airway

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In preparing for oropharyngeal airway suctioning, a nurse must gather all necessary equipment, including a suction unit with tubing, a prepackaged suction kit, sterile gloves, water or saline for irrigation, a water-soluble lubricant, and additional personal protective equipment (such as a gown, mask, and goggles) to control infections.
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Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

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Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
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Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics
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A hydrogel-driven microfluidic suction pump with a high flow rate.

Jaedeok Seo1, Cong Wang, Sooyoung Chang

  • 1Department of Mechanical Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, Republic of Korea. sortpark@sogang.ac.kr wonjungkim@sogang.ac.kr.

Lab on a Chip
|April 10, 2019
PubMed
Summary
This summary is machine-generated.

We developed a novel, non-powered hydrogel pump for microfluidic devices, offering high flow rates and long-term operation. This versatile pump enables portable power generation, showcasing a breakthrough for microfluidic applications.

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Area of Science:

  • Materials Science
  • Chemical Engineering
  • Biomedical Engineering

Background:

  • Microfluidic devices require efficient and portable fluid handling systems.
  • Existing pumps often rely on external power sources, limiting portability.
  • Superabsorbent polymers offer potential for passive fluid manipulation.

Purpose of the Study:

  • To develop a portable, non-powered, long-term working suction pump for microfluidic applications.
  • To achieve a high flow rate and significant absorption volume using a superabsorbent polymer.
  • To demonstrate the pump's utility in a portable power generation system.

Main Methods:

  • Designed a suction pump utilizing a superabsorbent polymer within a housing with porous fins.
  • Experimentally measured the flow rate and absorption volume of the developed pump.
  • Integrated the hydrogel pump with a reverse electrodialysis (RED) device to create a portable power generator.

Main Results:

  • The hydrogel pump achieved a high flow rate exceeding 80 μl min-1 and an absorption volume of approximately 20 ml.
  • The pump demonstrated long-term working capability.
  • The integrated portable power generator produced an output density of ~70 μW cm-2 for over an hour using KCl solutions.

Conclusions:

  • The proposed hydrogel pump offers a versatile, non-powered solution for microfluidic fluid handling.
  • The pump's design principles enable high performance and long-term operation.
  • This technology presents a breakthrough for developing self-powered portable microfluidic systems.