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Updated: Jan 26, 2026

Respirometric Oxidative Phosphorylation Assessment in Saponin-permeabilized Cardiac Fibers
Published on: February 28, 2011
New Dammarane-type Saponins from Gynostemma pentaphyllum
Po-Yen Chen1,2, Chih-Chao Chang3, Hui-Chi Huang4
1Division of Chinese Materia Medica Development, National Research Institute of Chinese Medicine, Taipei 112, Taiwan. peik35@gmail.com.
Abstract:
Six new dammarane-type saponins, gypenosides CP1-6 (16), along with 19 known compounds 7⁻25, were isolated and characterized from the aerial parts of Gynostemma pentaphyllum. Among these compounds, eight dammarane-type saponins, 2, 5, 6, 7, 11, 12, 13, and 15, exhibited the greatest antiproliferative effects against two human tumor cell lines (A549 and HepG2).
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