Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Polymers02:34

Polymers

40.6K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
40.6K
Polymers02:34

Polymers

23.2K
23.2K
Molecular Shape and Polarity03:37

Molecular Shape and Polarity

75.0K
Dipole Moment of a Molecule
75.0K
VSEPR Theory and the Basic Shapes02:52

VSEPR Theory and the Basic Shapes

84.3K
Overview of VSEPR Theory
84.3K
Molecular Shapes01:18

Molecular Shapes

61.6K
Molecules have characteristic shapes that are crucial for their function. The arrangement of various electron groups around the central atom dictates their molecular geometry. Electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between the electron pairs by maximizing the distance between them. The valence electrons form either bonding pairs, located primarily between bonded atoms, or lone pairs.
Two regions of electron density in a diatomic...
61.6K
First Derivatives and the Shape of a Graph01:22

First Derivatives and the Shape of a Graph

68
In calculus, the concept of the first derivative plays a crucial role in understanding the behavior of a function over its domain. The first derivative, denoted as f’(x), provides insight into how a function changes at any given point, much like a cyclist adjusting speed along a winding trail. By analyzing the first derivative, mathematicians can determine where a function is increasing, decreasing, or reaching critical points.The first derivative provides a precise method for classifying...
68

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SinusNet+: Deep Condition-Label-Free Segmentation of Maxillary Sinus Conditions in CBCT images.

Dento maxillo facial radiology·2026
Same author

Reusable octenidine-loaded polyetherimide nanofiber filter membranes for efficient air filtration and airborne bacteria inactivation.

Journal of hazardous materials·2026
Same author

Corrigendum to 'Multi-Task Deep Learning for Sex and Age Estimation from Panoramic Radiographs in a Brazilian Young Population': [International Dental Journal Volume 76, Issue 2, April 2026, 109381].

International dental journal·2026
Same author

Hydrophobic Polymer-Coated and Uncoated ZIF-67/Alumina Membrane for Volatile Organic Compound Degradation and CO<sub>2</sub> Adsorption Capture.

ChemSusChem·2026
Same author

Multi-Task Deep Learning for Sex and Age Estimation from Panoramic Radiographs in a Brazilian Young Population.

International dental journal·2026
Same author

Dual functional biodegradable PLA/ZIF-67 nanofiber air filter for instantaneous removal of toluene and particulate matter.

Journal of environmental management·2025

Related Experiment Video

Updated: Jan 26, 2026

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

11.3K

Plateau-Shaped Flexible Polymer Microelectrode Array for Neural Recording.

Jun-Min Kim1, Changkyun Im2, Woo Ram Lee3

  • 1Medical Device Research Center Medical & Health Device Division, Korea Testing Laboratory, Seoul 52852, Korea. junmin83@gmail.com.

Polymers
|April 11, 2019
PubMed
Summary

Flexible polymer microelectrode arrays (MEAs) with plateau-shaped electrodes improve neural recordings from the spinal cord by ensuring close contact and minimizing signal degradation. This novel design enhances signal-to-noise ratio for more reliable neural data acquisition.

Keywords:
PDMSPDMS etchingfabricationmultielectrode array (MEA)plateau-shaped electroderecessed electrodespinal cord signal recordingunderexposure

More Related Videos

Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording
09:58

Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording

Published on: February 12, 2020

14.1K
Construction and Implementation of Carbon Fiber Microelectrode Arrays for Chronic and Acute In Vivo Recordings
07:37

Construction and Implementation of Carbon Fiber Microelectrode Arrays for Chronic and Acute In Vivo Recordings

Published on: August 5, 2021

4.4K

Related Experiment Videos

Last Updated: Jan 26, 2026

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

11.3K
Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording
09:58

Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording

Published on: February 12, 2020

14.1K
Construction and Implementation of Carbon Fiber Microelectrode Arrays for Chronic and Acute In Vivo Recordings
07:37

Construction and Implementation of Carbon Fiber Microelectrode Arrays for Chronic and Acute In Vivo Recordings

Published on: August 5, 2021

4.4K

Area of Science:

  • Neuroscience
  • Materials Science
  • Biomedical Engineering

Background:

  • Conventional polymer microelectrode arrays (MEAs) exhibit poor conformability and electrode-neuron gaps, leading to signal degradation, especially in fiber bundles like the spinal cord.
  • These gaps are problematic for neural recording in the spinal cord, unlike in the brain where tissue can repopulate the gaps.

Purpose of the Study:

  • To develop and evaluate flexible polydimethylsiloxane (PDMS)-based MEAs with plateau-shaped microelectrodes for improved neural recordings.
  • To enhance the conformability and electrode-tissue interface of MEAs for minimizing injury and signal loss.

Main Methods:

  • Fabrication of flexible PDMS-based MEAs with plateau-shaped microelectrodes (130 μm diameter, 300 μm spacing).
  • Characterization of electrode 3D profile, impedance, and performance in vivo.
  • Utilizing PDMS with a Young's modulus similar to soft tissues for high conformability.

Main Results:

  • Plateau-shaped electrodes achieved a tight connection with neurons, eliminating gaps and improving signal-to-noise ratio compared to recessed electrodes.
  • Minimized injury due to MEA movement owing to PDMS conformability.
  • Successful simultaneous multi-channel neural recordings from the rodent spinal cord were achieved.

Conclusions:

  • The proposed plateau-shaped microelectrodes on flexible PDMS MEAs offer a significant improvement for neural recording, particularly in challenging tissues like the spinal cord.
  • This fabrication method enhances the electrode-tissue interface, leading to more reliable and higher-quality neural signal acquisition.