Related Experiment Video

Updated: Jan 26, 2026

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management
09:03

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management

Published on: March 28, 2025

1.1K

Managing neonatal pain in the era of non-invasive respiratory support

Manon Tauzin1, Xavier Durrmeyer2

  • 1Neonatal Intensive Care Unit, Centre Hospitalier Intercommunal de Créteil, Créteil, France.

Seminars in Fetal & Neonatal Medicine
|April 11, 2019
PubMed

Insights

Non-invasive ventilation (NIV) is crucial for premature infants, but it may cause pain. This review examines NIV optimization, drug use, and risks/benefits to improve pain management in neonates.

Area of Science:

  • Neonatology
  • Pediatric Critical Care
  • Pain Management

Background:

  • Non-invasive ventilation (NIV) is the primary respiratory support for premature infants with respiratory distress.
  • While lung-protective, NIV can cause pain and discomfort, necessitating careful management.
  • Non-pharmacological interventions are recommended for all premature infants but are outside the scope of this review.

Purpose of the Study:

  • To review current evidence and identify knowledge gaps in pain management for premature infants receiving NIV.
  • To explore strategies for optimizing NIV to minimize patient discomfort.
  • To assess the use of analgesic and sedative drugs in specific NIV contexts.

Main Methods:

  • Review of existing literature on pain management in premature infants on NIV.
  • Analysis of evidence related to NIV optimization (positive pressure, interface, synchrony).
  • Evaluation of sedative/analgesic drug use for surfactant administration and prolonged pain management.

Main Results:

  • Limited robust evidence exists for specific pain management strategies.
  • Optimization of NIV parameters may reduce discomfort.
  • Risks and benefits of various analgesic/sedative drugs require further investigation.

Conclusions:

  • Caregivers should critically evaluate their current practices regarding pain management during NIV.
  • Further research is needed to establish evidence-based guidelines for NIV-associated pain in neonates.
  • A multimodal approach, considering NIV settings and pharmacological options, is essential.

Keywords:
DexmedetomidineHigh flow nasal cannulaLess invasive surfactant administrationNasal injuryNasal maskNeurally adjusted ventilatory assistParacetamolPremature infantPropofol

More Related Videos

Chuzhen Therapy as a Non-Invasive Traditional Chinese Therapy for Neck Pain04:24

Chuzhen Therapy as a Non-Invasive Traditional Chinese Therapy for Neck Pain

Published on: June 6, 2025

1.2K
Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram09:00

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

Published on: July 7, 2023

4.4K

Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.5K
Self-Help Support Groups01:28

Self-Help Support Groups

Self-help support groups are voluntary, community-based organizations that provide a platform for individuals with shared concerns to exchange support, insights, and practical strategies for coping with life challenges. Typically led by group members or paraprofessionals, these groups form a cornerstone of mental health care, especially in reaching populations that are underserved by traditional healthcare systems.
Accessibility and Cost-Effectiveness
One of the primary strengths of self-help...
341
Anatomy of Respiratory System II: Lower Respiratory Tract01:31

Anatomy of Respiratory System II: Lower Respiratory Tract

The lower respiratory tract is anatomically composed of several vital structures, including the larynx, trachea, bronchial tree, alveoli, lungs, and pleurae. Each component has a specific function, and all are intricately connected to ensure efficient respiration.
The Larynx
It is located between the pharynx and the trachea, acts as a passageway for air, and hosts several critical structures, such as the epiglottis, vocal cords, and glottis. The epiglottis acts as a gateway, guiding food to the...
3.5K
Pain01:20

Pain

Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.3K
The Respiratory System01:16

The Respiratory System

The respiratory system is comprised of the organs that enable breathing. Air enters the nostrils and mouth, followed by the pharynx (throat) and larynx (voice box), which lead to the trachea (windpipe). In the thoracic cavity, the trachea splits into two bronchi that allow air to enter the lungs. The bronchi split into progressively smaller bronchioles and terminate in small groups of tiny sacs in the lungs called alveoli, where gas exchange occurs.
89.2K
Anatomy of Respiratory System I: Upper Respiratory Tract01:29

Anatomy of Respiratory System I: Upper Respiratory Tract

The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
5.1K