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Updated: Jan 26, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
The Hypervirulent Strain of Clostridium Difficile: NAP1/B1/027 - A Brief Overview
Rawish Fatima1, Muhammad Aziz2
1Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
Abstract:
Clostridium difficile is a gram-positive bacterium notorious for causing epidemic diarrhea globally with a significant health burden. The pathogen is clinically challenging with increasing antibiotic resistance and recurrence rate. We provide here an in-depth review of one particular strain/ribotype 027, commonly known as NAP1/B1/027 or North American pulsed-field gel electrophoresis type 1, restriction endonuclease analysis type B1, polymerase chain reaction ribotype 027, which has shown a much higher recurrence rate than other strains.
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