Related Experiment Video
Updated: Jan 26, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
[Swallowing in the elderly : Physiological changes, dysphagia, diagnostics and treatment]
P Muhle1,2, S Suntrup-Krueger3,4, R Wirth5
1Klinik für Neurologie mit Institut für Translationale Neurologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Deutschland. paul.muhle@ukmuenster.de.
Aging affects swallowing structures, increasing dysphagia risk and leading to serious health issues like pneumonia and malnutrition. Early evaluation and multidisciplinary treatment are crucial for managing age-related swallowing difficulties.
Area of Science:
- Gerontology
- Gastroenterology
- Otolaryngology
Background:
- Aging causes physiological and pathological changes impacting swallowing structures.
- These changes elevate the risk of dysphagia, potentially leading to pneumonia, malnutrition, dehydration, reduced quality of life, and mortality.
Purpose of the Study:
- To review the impact of aging on swallowing.
- To discuss diagnostic methods for dysphagia.
- To outline available treatment strategies for age-related dysphagia.
Main Methods:
- Literature review on aging and swallowing.
- Discussion of clinical and instrumental swallowing assessments.
- Overview of dysphagia management approaches.
Main Results:
- Age-related changes significantly increase dysphagia prevalence and associated risks.
- Clinical swallowing tests and instrumental evaluations like endoscopic swallowing evaluation aid in diagnosis.
- Treatment options are diverse, including dietary modifications, exercises, and nutritional support.
Conclusions:
- Age-related dysphagia necessitates comprehensive evaluation and tailored treatment plans.
- Multidisciplinary collaboration is essential for optimal patient outcomes.
- Interventions aim to mitigate risks and improve quality of life for affected individuals.
Related Concept Videos
Upper GI Series: Barium Swallow
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
Physiological Barriers
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...
Liver Physiology
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
The Physiology of Taste
Physiology of Emotion
Autonomic Nervous System
The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...
Physiology of Urine Formation
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...

