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Analysis of 2897 hospitalization events for patients with chronic kidney disease: results from CKD-JAC study

Satoshi Iimuro1, Tetsuji Kaneko2, Yasuo Ohashi3

  • 1Teikyo Academic Research Center, Teikyo University, 2-11-1, Kaga, Itabashi-ku, Tokyo, Japan. siitky@gmail.com.

Clinical and Experimental Nephrology
|April 11, 2019
PubMed

Insights

Patients with chronic kidney disease (CKD) face significantly higher hospitalization rates, especially those with diabetes. CKD progression and diabetes increase risks for various conditions, highlighting a vulnerable population.

Area of Science:

  • Nephrology
  • Public Health
  • Epidemiology

Background:

  • Chronic kidney disease (CKD) is a known risk factor for severe renal and cardiovascular outcomes.
  • Limited data exist on hospitalization causes in maintenance-phase CKD patients.
  • This study addresses this gap by analyzing hospitalization data in CKD patients.

Purpose of the Study:

  • To aggregate hospitalization data in CKD patients.
  • To identify high-risk populations for hospitalization.
  • To compare hospitalization rates in CKD patients versus the general population.

Main Methods:

  • Post hoc analysis of the CKD-Japan cohort study.
  • Involved 2966 CKD patients with a median follow-up of 3.9 years.
  • Examined hospitalization reasons and analyzed risk factors.

Main Results:

  • CKD patients experienced hospitalization 17.1-fold higher than the general population.
  • Kidney, eye, and heart-related admissions were most common.
  • Hospitalization risk increased with CKD stage and diabetes presence; diabetes significantly elevated events.

Conclusions:

  • CKD patients, particularly those with diabetes, are highly susceptible to hospitalization.
  • These findings aid in predicting prognosis for CKD patients.
  • Diabetes exacerbates hospitalization risk more than CKD stage alone for cardiovascular events.
Abstract

Keywords:
Cardiovascular diseaseDiabetes mellitusDiabetic kidney diseaseJapanese patient survey 2008Pre-renal replacement therapy

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