[Neuropathological aspects of chronic diseases]

Practically all diseases of bodily organs may lead to quantitatively and qualitatively differing alterations of the central and periphal nervous system. These are connected to the basic disease on one side, to compications on the other. The preliminary condition for the appearance of encephalopathies following bodily diseases lies mostly in a disturbance of the blood-brain and blood-liquor barrier. No close correlation exists usually between psychiatric and nervous syndromes and pathomorphological findings. However, the findings are often characteristical, although not specifical. Especially the findings in uraemia, liver diseases, rheumatic and so-called pararheumatic diseases (collagenoses) are discussed.