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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Pregnancy denial and early infant development: a case-control observational prospective study
Julie Auer1, Coralie Barbe2, Anne-Laure Sutter3
1Service de Psychothérapie de l'enfant et de l'adolescent, Pôle Femme-Parents-Enfant, Av du Gl Koenig, Centre Hospitalier Universitaire, 51092, Reims Cedex, France.
This study investigates pregnancy denial, defined as late recognition of pregnancy. It explores how this impacts infant development, attachment, and mother-infant interactions over 18 months.
Area of Science:
- Psychology
- Developmental Psychology
- Maternal-Fetal Medicine
Background:
- Pregnancy denial involves a pregnant woman's non-recognition of her pregnancy, often with minimal physical changes.
- This study defines pregnancy denial as a late pregnancy declaration (after 20 weeks) or lack of objective pregnancy perception.
- A retrospective clinical trial registration (NCT02867579) was established on August 16, 2016.
Purpose of the Study:
- To explore the relationship between pregnancy denial and infant development.
- To investigate the impact of pregnancy denial on infant attachment patterns.
- To examine the influence of pregnancy denial on early mother-infant dyadic interactions.
Main Methods:
- A prospective case-control study design comparing 70 dyads with maternal pregnancy denial to 70 control dyads.
- Inclusion of 140 mother-infant dyads recruited nationally across 10 centers in France.
- Standardized follow-up over 18 months and 5 visits, measuring infant attachment, mother-infant interaction quality, and infant development.
Main Results:
- Data collection and analysis are ongoing.
- Results will elucidate the effects of pregnancy denial on key developmental outcomes.
- Findings will provide insights into the pathogenesis and consequences of pregnancy denial.
Conclusions:
- This research aims to understand the origins of pregnancy denial.
- The study will examine the consequences of pregnancy denial on infant development and early mother-infant interactions.
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