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Updated: Jan 26, 2026

Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics
Published on: December 1, 2023
A Computational Model of Tumor Growth and Anakoinosis
Pan Pantziarka1,2, Lina Ghibelli3, Albrecht Reichle4
1The George Pantziarka TP53 Trust, London, United Kingdom.
Abstract:
Anakoinosis is a new cancer treatment paradigm that posits a key role for communicative reprogramming within tumor systems. To date no mathematical or computational models of anakoinosis have been developed. Here we outline the NEATG_A system, a first computational model of communicative reprogramming. The model recapitulates key features of real tumor systems and responses to both traditional cytotoxic treatments and biomodulatory/anakoinotic treatments. Results are presented and discussed, particularly with respect to the implications for future cancer treatment protocols.
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