Related Experiment Video
Updated: Jan 26, 2026

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
Outcomes of Corneal Transplantation Using Donor Corneas Retrieved From Snakebite Victims
Pragnya Rao Donthineni1, Sunita Chaurasia1,2, Prashant Garg1,2
1Tej Kohli Cornea Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Purpose:
To report the outcomes of corneal transplantation using donor corneas retrieved from snakebite victims.
Methods:
This study was a retrospective analysis of 30 corneal transplants performed from 2014 to 2016 using donor corneas retrieved from snakebite victims. The details of the donor corneal characteristics and the transplant recipients were collected from the eye bank and the medical records department.
Results:
The mean age of the donors was 30.4 ± 17.5 years. The median death-to-preservation time was 3.3 hours [interquartile range: 1.3-5.6 hours]. Ninety percent (27/30) of the corneas were evaluated as optical grade, and 10% (3/30) of the corneas were deemed as therapeutic grade. The mean endothelial cell density on specular microscopy of the donor corneas was 2943 ± 615 cells/mm, and median corneal thickness was 514 μm (interquartile range: 506-520). Seventy-five percent of the corneas transplanted had cleared, with a mean follow-up duration of 1.5 ± 1.0 years (range: 0.4-3.7) years and mean logarithm of the minimum angle of resolution (LogMAR) visual acuity of 0.51 ± 0.27 (range: 0-1.2) at the last follow-up.
Conclusions:
The donor corneas retrieved from snakebite victims are apparently safe and suitable for transplantation, and screening for such donor corneas should include a thorough examination of ocular adnexa to rule out local envenomation before corneal retrieval in addition to the routine evaluation protocol.
Related Concept Videos
Retrieval
Recall involves accessing information without cues, such as during an essay test, where individuals must retrieve facts and concepts from memory unaided. Another example is remembering the name of a colleague...
ER Retrieval Pathway
The ER uses many checkpoints to prevent the entry of incorrectly folded or a resident protein as cargo onto a transport vesicle. These mechanisms...
Predicting Reaction Outcomes
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Guidelines for Writing Outcome
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

