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Updated: Jan 26, 2026
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Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
Published on: January 27, 2018
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Scalp bacterial shift in Alopecia areata
Daniela Pinto1,2,3, Elisabetta Sorbellini2,3, Barbara Marzani1,2,3
1Giuliani SpA, Milan, Italy.
Plos One
|April 12, 2019
Summary
Scalp microbial dysbiosis, specifically increased Propionibacterium and decreased Staphylococcus, is linked to Alopecia Areata (AA). This study reveals significant bacterial shifts in AA patients, impacting hair growth and scalp health.
Area of Science:
- Microbiology
- Dermatology
- Genetics
Background:
- Microbial dysbiosis is increasingly implicated in various skin conditions.
- Limited research exists on the scalp microbiome's role in hair growth disorders like Alopecia Areata (AA).
Purpose of the Study:
- To investigate and compare bacterial communities in healthy scalps versus those affected by Alopecia Areata.
- To identify specific bacterial species or genera associated with AA.
Main Methods:
- Utilized sequencing profiling to analyze bacterial populations in scalp samples from AA patients and healthy controls.
- Compared the relative abundance of bacterial genera and species between the two groups.
Main Results:
- Alopecia Areata (AA) subjects showed a significant increase in Propionibacterium and a decrease in Staphylococcus compared to controls.
- Propionibacterium acnes abundance was significantly higher in AA patients.
- Staphylococcus epidermidis abundance was significantly lower in AA patients, while Staphylococcus aureus showed no significant change.
Conclusions:
- The study provides the first evidence of a distinct microbial shift on the scalps of patients with Alopecia Areata.
- These findings suggest a role for microbial dysbiosis in the pathogenesis of AA and hair disorders.
- Further comprehensive studies are warranted to explore the involvement of the scalp microbiome in hair loss conditions.
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