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Airway Malformations and Bronchiectasis: A Pediatric Study
1Pediatric Respiratory, San Diego, CA, USA.
Insights
Congenital airway malformations rarely lead to bronchiectasis in children. This study found a low coexistence, suggesting effective preventative treatments for respiratory infections in pediatric patients with airway anomalies.
Area of Science:
- Pediatric Pulmonology
- Medical Informatics
Background:
- Congenital airway malformations are typically diagnosed in early childhood.
- Bronchiectasis development alongside lower airway malformations is documented, primarily in adults.
- The co-occurrence of these conditions in pediatric populations is not well-established.
Purpose of the Study:
- To investigate the frequency of bronchiectasis in pediatric patients with congenital airway malformations.
- To determine if younger patients with airway anomalies commonly develop bronchiectasis.
Main Methods:
- Defined International Classification of Diseases, Ninth Revision (ICD-9) codes for airway anomalies and bronchiectasis.
- Searched a children's hospital electronic medical records system for patients with airway anomalies.
- Cross-referenced airway database with ICD codes for bronchiectasis to identify co-occurring cases.
Main Results:
- Out of 844 patients with airway anomalies and 117 with bronchiectasis (August 2009-September 2014), only 3 patients had both conditions.
- The coexistence of bronchiectasis was found to be low in the studied pediatric population with upper airway anomalies.
Conclusions:
- The low incidence suggests current management strategies are effective in preventing recurrent lower respiratory tract infections in children with airway anomalies.
- Further research is recommended to evaluate strategies for preventing aspiration and lower respiratory tract infections.
- Database integration platforms are valuable for identifying pediatric patient cohorts for further study.
Abstract:
Congenital airway malformations are most often identified in early childhood. The development of bronchiectasis in association with malformations of the lower airway has been described, particularly among adult patients. The coexistence in a pediatric population of these conditions is not well described. This study was conducted to identify whether younger patients with airway malformations commonly develop bronchiectasis. International Classification of Diseases, Ninth revision (ICD-9 codes) were defined for airway anomalies and bronchiectasis. The electronic medical records system of a children's hospital was then searched for the number of patients with upper airway anomalies with or without bronchiectasis. The airway database was then cross referenced with the ICD codes for bronchiectasis to identify patients with both conditions. There were 844 patients with airway anomalies and 117 with bronchiectasis in the electronic system during the time period of August 1, 2009 to September 30, 2014. There was only 3 patients identified with both bronchiectasis and airway anomalies. The coexistence of bronchiectasis is low among the pediatric population with upper airway anomalies studied. This would suggest that the children with airway anomalies have been treated with strategies that are effective in the prevention of recurrent lower respiratory tract infection. Further study may be done to define the effectiveness of various strategies in preventing aspiration and lower respiratory tract infection. In addition, this methodologic technique utilizing database integrative platforms is useful in the identification of patients for further study and to identify the coexistence of pediatric conditions.
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