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Updated: Jan 26, 2026

A Novel Biaxial Testing Apparatus for the Determination of Forming Limit under Hot Stamping Conditions
Published on: April 4, 2017
Limits of current male fertility testing
Sergio Oehninger1, Willem Ombelet2
1Sher Fertility Institute, New York, New York.
Abstract:
In the current approach to male fertility testing, basic semen analysis has limitations as a predictor of fertility status, and the technology is fraught with variability. Nonetheless, it remains the cornerstone of the evaluation of the male infertility, and we recommend adherence to most recent World Health Organization guidelines. Although the current sperm function tests (bioassays) have important drawbacks, they are still valuable as research tools. Sperm quality assays with analysis of sperm DNA fragmentation need further investigation before they can be recommended for routine clinical use. The answer to the many current challenging questions relies on identifying spermatogenesis pathologies and the resulting sperm dysfunctions at the cellular and molecular levels. New discoveries may bring answers or new avenues to explore.
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