Related Experiment Video
Updated: Jan 26, 2026

Bioassays for Monitoring Insecticide Resistance
Published on: December 30, 2010
Discovery of nitropyridyl-based dichloropropene ethers as insecticides
Aiping Liu1, Minhua Liu2, Hong Yu2
1National Engineering Research Center for Agrochemicals, Hunan Research Institute of Chemical Industry, Changsha 410007, People's Republic of China; Hunan Province Key Laboratory for Agrochemicals, Changsha 410014, People's Republic of China.
Abstract:
A series of nitropyridyl-based dichloropropene ethers were prepared and evaluated for their insecticidal activities against main lepidopteran pests such as M. separate, P. xylostella and P. litura. The compounds showed a broad-spectrum of remarkable insecticidal activities. Especially 4a (2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-nitro-2-pyridyloxy]propyl ether) and 11a (2-(4-(3-(2,6-dichloro-4-((3,3-dichloroallyl)oxy)phenoxy)propoxy)phenoxy)-5-nitropyridine) displayed potent activities comparable to that of Pyridalyl, the only commercialized dichloropropene ether insecticide thus far. The structure-activity relationship was also discussed.
Related Concept Videos
Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis
Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
Preparation of Ethers by Alcohol Dehydration
In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
Structure and Nomenclature of Ethers
Ethers are organic compounds with an ether functional group which is characterized by an oxygen atom connected to two — identical or different — alkyl, aryl, or vinyl groups. The C–O–C linkage in dimethyl ether — the simplest ether — has an approximately tetrahedral bond angle of 110.3 degrees. The oxygen atom is sp3- hybridized, with the C–O distance being about 140 pm.
Classification of Ethers
Based on their attached substituent...
Crown Ethers
Physical Properties of Ethers
An ether molecule has a net dipole moment due to the polarity of C–O bonds. Subsequently, boiling points of ethers are lower than those of alcohols of comparable molecular weight and slightly higher than those of hydrocarbons of comparable molecular weight (Table 1).
Ethers can act as hydrogen bond acceptors, making them more water-soluble than hydrocarbons, but since ethers cannot act as hydrogen bond donors, they are much less soluble in water than alcohols. Ethers are considered...
Autoxidation of Ethers to Peroxides and Hydroperoxides
Drug Discovery: Overview

