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Updated: Jan 26, 2026

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Enzymatic activation of indolequinone-substituted 5-fluorodeoxyuridine prodrugs in hypoxic cells

Yota Jiho1, Ryohsuke Kurihara1, Kiyohiko Kawai2

  • 1Department of Chemistry and Biological Science, College of Science and Engineering, Aoyama Gakuin University, 5-10-1 Fuchinobe, Chuo-ku, Sagamihara 252-5258, Japan.

Bioorganic & Medicinal Chemistry Letters
|April 13, 2019
PubMed

Keywords:
Enzymatic activationProdrugReductaseTumor hypoxia

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