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Draft Genome Sequences of 48 Vancomycin-Resistant Enterococcus faecium Strains Isolated from Inpatients with
Zulema Udaondo1, Thidathip Wongsurawat1, Piroon Jenjaroenpun1
1Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Microbiology Resource Announcements
|April 13, 2019
Summary
This study presents the genome sequences of 48 vancomycin-resistant Enterococcus faecium (VREfm) isolates. These VREfm strains were obtained from patients with bacteremia, aiding in understanding these significant hospital-acquired infections.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Vancomycin-resistant Enterococcus faecium (VREfm) is a significant pathogen responsible for hospital-acquired infections.
- VREfm bloodstream and urinary tract infections pose a major clinical challenge due to limited treatment options.
Purpose of the Study:
- To generate draft genome sequences for 48 VREfm isolates.
- To provide genomic data for VREfm strains implicated in bacteremia.
Main Methods:
- Whole-genome sequencing of 48 VREfm isolates.
- Bioinformatic analysis of generated draft genomes.
Main Results:
- Successfully obtained draft genome sequences for all 48 VREfm isolates.
- Genomic data provides a foundation for further investigation into VREfm virulence and resistance.
Conclusions:
- The availability of these draft genome sequences facilitates research into VREfm epidemiology and pathogenesis.
- This genomic resource supports efforts to combat VREfm nosocomial infections.
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